Histone post-translational modifications (PTMs ... the precise mechanisms by which SCFAs regulate chromatin and gene expression remain unclear, necessitating further research to uncover their ...

Short-chain fatty acids (SCFAs) like propionate and butyrate are critical byproducts of dietary fiber digestion. These ...

The role of histone modifications in atherosclerosis is ... and sugar can induce epigenetic changes that affect gene expression and overall health. For example, short-term exposure to air ...

Histone post-translational modifications are ... the H3K79 methyltransferase DOT1L has opposite effects on autosomal and X-linked gene expression depending on local chromatin enrichment in ...

Thus, the decline of estrogen levels or imbalance of these metabolites affects gene expression and underlying brain functions. In the present review, we discussed the importance of DNA methylation and ...

Modification of histone proteins by serotonin in the nucleus ... next investigated whether neurons in the TMN show rhythmic gene expression, and whether this depends on H3Q5his.

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

Heroes, Warriors, and Martyrs—may be biologically imprinted in our DNA. Science, psychology, and epigenetics reveal the roots ...

The science of skin ageing has entered a transformative phase, thanks to advancements in epigenetics-the study of biological mechanisms that control gene expre ...

Cancer’s epigenetic landscape, a labyrinthine tapestry of molecular modifications, has long captivated researchers with its profound influence on gene expression and cellular fate. This review ...

Dopamine, serotonin, and histamine carry messages between neurons. They can also influence circadian gene expression ...

In a groundbreaking study led by Dr. Ying Chen and her team from Ruijin Hospital, Shanghai Jiao Tong University School of ...