An MTF2-containing subcomplex of Polycomb Repressive Complex 2 promotes cell cycle progression through repression of D-type cyclin expression in certain cellular contexts.

The PIF/Harbinger-derived ADF-IL protein recruits KAT2B to drive its nuclear translocation and local chromatin acetylation, ...

Ph.D. Program in Medical Neuroscience, College of Medical Science and Technology, Taipei Medical University and National Health Research Institutes, Taipei 110, Taiwan International Master Program in ...

Right next to that glutamine is a lysine, H3K4, that is a common site for methylation. Methylation at H3K4 promotes transcription of genes near the histone, and marking H3Q5 with a serotonin helps ...

Dunn, recently carried out a study exploring how DNA methylation, an epigenetic modification that entails the addition of a methyl group to the DNA, contributes to the well-documented relationship ...

Introduction: DNA methylation inhibitors have been approved for the prevention of Acute Myeloid Leukemia (AML), and their safety profile is not fully characterized. This study was aimed at evaluating ...

Biochemistry and Molecular Biology, Indiana University School of Medicine (IUSM), 635 Barnhill Drive, Medical Science Building, Indianapolis, Indiana 46202-5122, United States ...

Lysine lactylation is a newly discovered protein post-translational modification that plays regulatory roles in cell metabolism, growth, reprogramming, and tumor progression. It utilizes lactate as ...

Histone chaperones have an important role in controlling histone dynamics at the fork. The maintenance of DNA methylation and histone modifications is interconnected at the replication fork.

It is important to note that although we have some idea about the propagation of DNA methylation and models ... Figure 4: Propagation of histone 3 lysine 27 trimethylation by polycomb repressive ...

Amino acids were often highest in cool-season grasses and lowest in teff. Moderate amino acid levels were present in alfalfa. Despite these differences, we compared the lysine amino acid content in ...