Recent studies using genetically engineered mouse strains have shed new light on this problem; the Hippo signalling pathway, first elucidated as a regulator of organ size in Drosophila ...

It has long been understood that the Hippo pathway plays a critical role in the development of a wide range of diseases. Although once seen as an elusive pathway, emerging novel data and research ...

The researchers also looked at how PI5P4K activity influenced other components of the hippo pathway and found that reduced ...

The Hippo pathway is a group of proteins that work together to control organ size and cell fate, and exists in all multicellular animals on Earth. In addition, when it is mutated in humans it can ...