In the curative trial, VPA was administered for 14 days, followed by DF for an additional 14 days. The results demonstrated that DF supplementation normalized body weight, liver biomarkers and ...

Figure 1. During sepsis, liver macrophages (Kupffer cells) in hepatic sinusoids synthesize large amounts of inflammatory cytokines (TNF-α, IL-6, IL-1β) through the TLR4-MyD88/NF-κB pathway. Moreover, ...

Massive infiltration of liver sinusoids by lymphoma cells (Figure 1) and NRH (Figures 1 and 2) was confirmed. The patient was therefore diagnosed with primary splenic lymphoma and hepatic ...

Patricia F. Lalor, Ph.D.; 1 Jeff Faint, Ph.D.; 1 York Aarbodem, M.Sc.; 1 Stefan G. Hubscher, F.R.C.Path.; 1 David H. Adams, M.D., F.Med.Sci.1 1 Liver Research Group ...

As a metabolic center, the liver prevents inappropriate immune responses to abundant dietary antigens within the liver that could result in liver injury. This self-preservation mechanism can however ...