IN 1955 Rucknagel et al. 1 described a new abnormal hemoglobin in a Negro family in North Carolina. This hemoglobin, designated "I", migrated more rapidly than normal hemoglobin on filter-paper ...

Hemoglobin studies showed that although multiple components were observed on electrophoresis at pH 8.6, the γ chain was the only polypeptide chain found. Family study revealed that the father was ...