Of note, SB24 blocked ATP degradation by both soluble and cell surface CD39 as a 15kD monomeric nanobody. Dimerization via fusion to an immunoglobulin Fc portion further increased the blocking potency ...

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.

The Price to Earnings (P/E) ratio, a key valuation measure, is calculated by dividing the stock's most recent closing price by the sum of the diluted earnings per share from continuing operations ...

Run a brief analysis at the single-cell level, let’s use the common Seurat pipeline. set.seed(12345) sc <- CreateSeuratObject(counts = sc.counts, project = proj.name, meta.data = sc.meta) sc ## An ...

With increasing interest in developing antifibrotic therapies, there is a need for cell lines that preserve the in vivo phenotype of human HSCs to elucidate pathways of human hepatic fibrosis. We ...

In this review, we provide an overview of reporter cell lines established to characterize the human NR activities of a large panel of EDCs including natural as well as industrial compounds such as ...

Figure 1: Expression of WT-hTERT and DN-TERT in immortalized cell lines. Figure 2: Effects of WT-hTERT and DN-hTERT on telomerase activity. Figure 3: Effects of DN-hTERT expression on telomere length.

A 'pocket' on the protein cyclin B is responsible for ensuring that the steps of cell division take place in the correct order. Cell division is key for life. Every organism -- from the smallest ...