Abstract and Introduction Pathophysiology and Implications of Atherosclerosis Emerging Role of Statins Discussion References Current studies have questioned the relationship between CRP and LDL ...

HMG-CoA reductase inhibitors, commonly referred to as statins, are the cornerstone of pharmacologic reduction of elevated low-density lipoprotein cholesterol. LDL-C is the main contributor to ...

In patients with hypercholesterolemia, ezetimibe added to ongoing HMG-CoA reductase inhibitor therapy significantly lowered total cholesterol, LDL-C, apolipoprotein B, and triglycerides and ...

Do not take two doses at the same time. Simvastatin and atorvastatin are cholesterol-lowering medications classified as HMG-CoA reductase inhibitors. They lower cholesterol levels by preventing ...

HMG-CoA reductase inhibitors may impair the biosynthesis ot nonsterol isoprenes in a fashion analogous to that observed in mevalonic aciduria ...

aldosterone antagonists and HMG-CoA reductase inhibitors. Early antithrombotic administration at the time of STEMI diagnosis consists of non-enteric-coated aspirin 162 mg to 325 mg (unless ...

They work by inhibiting an enzyme in the liver called HMG-CoA reductase and by inhibiting ... that same effect of causing liver damage. PCSK9 inhibitors are a new class of medications that may ...

Concomitant cisapride, pimozide, ergots, lomitapide, HMG-CoA reductase inhibitors extensively metabolized by CYP3A4 (lovastatin or simvastatin). Concomitant colchicine (in renal or hepatic ...

These medications work by inhibiting an enzyme called HMG-CoA reductase, which plays a key ... heart disease and improving heart function. ACE inhibitors (Angiotensin-Converting Enzyme inhibitors ...