The World Health Organisation (WHO) has expressed deep concern about the funding pause for HIV programmes in low- and middle-income countries. US President Donald Trump recently ordered a funding ...

Table 1 shows the different classes of HIV inhibitors and the molecular processes they interrupt. Nucleoside Reverse Transcriptase Inhibitors (NRTIs) – Block viral DNA synthesis Non-Nucleoside Reverse ...

Human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infections represent critical global health challenges due to the high morbidity and mortality associated with co-infections. HIV, the ...

offering new insights into the relationship between mutation accumulation and epigenetic clocks. This suggests that epigenetic changes may track, rather than cause, aging, making it harder to reverse ...

The research also demonstrated that genetic mutations and epigenetic modifications could be used interchangeably to predict biological age, further cementing their connection. The study raises ...

"If somatic mutations are the fundamental driver of aging and epigenetic changes simply track this process, it's going to be a lot harder to reverse aging than we previously thought," added co ...

NRTI-resistance mutations & their mechanism of drug ... Stereogram for the 3D structure of HIV-1 reverse transcriptase in complex with a DNA template-primer and dTTP. The p66 subunit of HIV ...

A human strain of H5N1 bird flu isolated in Texas shows mutations enabling better replication in human cells and causing more severe disease in mice compared to a bovine strain. While the virus isn’t ...

In a recent study, they conducted a comprehensive analysis of cis-regulatory elements (CREs)—DNA sequences that control gene transcription. This research provides valuable insights into how CREs drive ...

A reverse mortgage is a loan, and an annuity is insurance Matt Webber is an experienced personal finance writer, researcher, and editor. He has published widely on personal finance, marketing ...

But Scripps Research scientists have now discovered that for some HIV vaccines, something else happens: after a few immunizations the immune system begins to produce antibodies against immune ...