This article highlights the role of bacterial glycosidases during infections, introduces the use of such enzymes as glycoengineering tools and discusses the potential of further studies in this ...

陈兴/戴鹏团队于2025年2月7日在Nature Communications上在线发表题为“Mutant glycosidases for labeling sialoglycans with high specificity and affinity”的研究论文，该工作报道了一类基于糖基水解酶突变策略的唾液酸化糖质亲和标记工具 GRABs。 亲和标记（Affinity ...

Laboratory of Computer-Aided Molecular Design, Division of Medicinal Chemistry, Otto-Loewi Research Center, Medical University of Graz, Neue Stiftingtalstr. 6/III, A-8010 Graz, Austria ...

1 Department of Medical Biochemistry, Molecular Biology, and Immunology, School of Medicine, University of Seville, Seville, Spain 2 Instituto de Biomedicina de ...

Laboratory for Sustainable Organic Synthesis and Catalysis, Department of Chemistry, Federal University of São Carlos-UFSCar, 13565-905 São Carlos, São Paulo, Brazil ...

In some cases, such as glycosidases, the substrate molecule also changes shape slightly as it enters the active site. The active site continues to change until the substrate is completely bound, at ...