Therefore, the main activity of ethanol is thought to be on glutamatergic and GABAergic signaling pathways, with an increase or decrease of function depending on the state (acute consumption, chronic ...

The mammalian neocortex is composed of a variety of cell types organized in a highly interconnected circuit. GABAergic neurons account for only about 20% of cortical neurons. However, they show ...

We seek agreement on a list of the essential features that differentiate the GABAergic interneurons of the neocortex, and encourage all investigators to use the same terms to describe the same ...

A study published in Science Signaling on the neural circuitry mediating addiction has made significant strides, particularly in understanding the intricat | Neuroscience ...

Many strokes affect neocortex, a 6-layered cellular sheet containing excitatory glutamatergic pyramidal projection neurons (~80%) and inhibitory local GABAergic interneurons (~18%) assembled into ...

Labroots is thrilled to announce the 13th Annual Event in the Neuroscience Virtual Event Series, streaming live on March 5th, 2025. Join us as we dive into the captivating world of neuroscience, ...

Although compounds with a combined cholinergic–glutamatergic action have been trialed, none has yet been successful in the later stages of development (Table 4). Consequently, combination ...

In this study, we investigated the neuronal activity of the dentate gyrus (DG) with optical imaging tools during sleep-wake cycles. We found that the activity of major glutamatergic cell populations ...

6 Prince of Wales Clinical School, University of New South Wales, Sydney, New South Wales, Australia Correspondence to Associate Professor Steve Vucic, Sydney Medical School Westmead, University of ...

This study presents solid evidence for distinct neurotransmitter release modalities between two subclasses of dopaminergic neurons in the olfactory bulb, highlighting an important finding that ...