Researchers can experimentally interrogate the function of one or more genes using knockout or knockdown tools. Although both approaches ultimately interfere with gene function, knockout and knockdown ...

Identify the clones that produce the desired knockdown effect and proceed with stable expression experiments to further analyze loss of gene expression. One particular plasmid design will not suit ...

1 Scientists have harnessed RNAi in the laboratory to selectively silence target gene expression, a technique known as gene knockdown. 8 By delivering dsRNA that are complementary to a target gene’s ...

Research led by Children's Hospital of Fudan University in China has found that a gene called pancreatic progenitor cell ...

Single IV administration of tau silencing gene therapy VY1706 significantly reduced tau mRNA and protein levels, with broad ...