a Department of Surgery, University of Heidelberg, Heidelberg, Germany, b Department of Immunochemistry, German Cancer Research Center, Heidelberg, Germany Dr B Sido, Department of Surgery, University ...
This project is in early development stage. Use at your own risk! Please expect bugs, incomplete features and breaking changes. That said, if you can try it out and provide feedback, that would help ...
Activity is expressed in nmol/(mg × min). The reaction mixture containing 50 mM potassium phosphate, 1 mM EDTA, cytosol sample, 10 mM GSH, GSSG reductase (2.4 U/mL) and 1.5 mM NADPH was incubated at ...
For GSH and GSSG were measured using a modified Ellman’s method (Vuolo et al., 2022). Samples were deproteinated (3 volumes 5% TCA, 12,000 × g, 5 min, 4°C) and analyzed in a 96-well format. For GSH ...
NPA7 reduced H 2 O 2-induced reactive oxygen species levels and increased GSH/GSSG ratio in HCMs. Silencing GC-A and MasR reversed NPA7’s effects. NPA7 activated the KEAP1-NRF2 pathway, enhancing NRF2 ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Ferroptosis, an iron-dependent form of ...
Migratory locusts display striking phenotypical plasticity. Gregarious locusts at high density can migrate long distances and cause huge economic losses of crops. By contrast, solitary locusts at low ...
Chronic exposure to hyperglycemia can lead to cellular dysfunction that may become irreversible over time, a process that is termed glucose toxicity. Our perspective about glucose toxicity as it ...