Secreted ADP activates the surrounding platelets and this is critical in creating the growing clot. The granules also secrete adhesion molecules such as fibrinogen as well as up-regulating adhesion ...

The investigator was not blinded to treatment assignment. Choice of glycoprotein IIb/IIIa inhibitor was at the discretion of the investigator. Glycoprotein IIb/IIIa inhibitors could be used in the ...

Sepsis is a life-threatening clinical syndrome characterized by multiorgan dysfunction caused by a dysregulated or over-reactive host response to infection. During sepsis, the coagulation cascade is ...

Expert Rev Clin Pharmacol. 2012;5(3):319-336. Finally, a recent study suggested that although prasugrel significantly reduces thrombotic events in patients with ACS undergoing PCI because of its ...

During four FDS procedures some thrombus formation was noted during operation that was completely resolved after the injection of a glycoprotein (GP) IIb/IIIa inhibitor, with no clinical impact. We ...