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6 天
综述:基于泛 G 蛋白偶联受体(GPCR)药物发现平台的传统药物研究进展
ONE - GO 生物传感器可测量不同 G 蛋白类型的 G α - GTP,通用性强,可在多种细胞类型中准确测量 G 蛋白激活。DCy - FIR 平台使用含有 300 种工程化潜在 GPCR - Gα 偶联组合的酵母菌株库,可高精度识别 GPCR 配体,对于研究传统药物成分的多靶点特性具有重要潜力。
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