Figure 1: Characterization of MLC/mIgf-1 transgenic mice. Figure 4: Intracellular signalling in MLC/mIgf-1 transgenic muscle. Figure 5: MLC/mIgf-1 expression attenuates age-related genetic changes ...

Background: Weightless bone loss is a common pathological phenomenon in weightless environments, yet its specific molecular mechanism remain incompletely elucidated. The aim of this study was to ...

通过对 PPI 网络的拓扑分析，筛选出 9 个关键靶点，包括 ALB、AKT1、TP53、VEGFA、MAPK3、EGFR、STAT3、CASP3 和 IGF1。 富集分析：GO 和 KEGG 通路富集分析显示，薯蓣皂苷元可能通过 PI3K-Akt 通路增强脂肪酸代谢，改善炎症反应。在 GO 分析中，富集的生物学过程与代谢调节 ...

Methods: We isolate primary nucleus pulposus cells (NPCs) and primary annulus fibrosus cells (AFCs) from rats as the target cells of rat insulin-like growth factor 1(IGF1), and verify the ...

编辑推荐：为阐明特发性肺动脉高压(IPAH)血管重塑中糖酵解异常调控机制，哈尔滨医科大学团队通过整合单细胞测序(scRNA-seq ...