Ferroptosis plays an essential role in chronic liver diseases, and cyclooxygenase-2 (COX-2) affects liver fibrosis through multiple mechanisms. However, research on COX-2 regulation of ferroptosis ...

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression. Ferroptosis, driven by excessive lipid peroxides and iron-dependent ...

Caption AZD1775 plays a role in the regulation of ferroptosis by dually targeting the cystine uptake and the WEE1-SETDB1 axis, while the activation of the p53-SLC7A11 cascade by Act. D augments ...