Polyunsaturated fatty acids (PUFAs) are important nutrients that play important roles in human health. In eukaryotes, PUFAs can be de novo synthesized through two independent biosynthetic pathways: ...

The sterol regulatory element-binding transcription factor 1 (SREBP-1), PPAR-γ coactivator-1α (PGC-1α), sirtuin 1 (SIRT1), fatty acid synthase (FASN), farnesyl-diphosphate farnesyltransferase 1 ...

As a key regulator of fatty acid biosynthesis, SREBP1a and SREBP1c induces their targets, including fatty acid synthase (FASN) and stearoyl coenzyme A desaturase 1 (SCD1). Peroxisome ...

Fatty acids are organic acids with at least one carboxyl (-C(=O)OH, -COOH or -CO2H) group and a long carbon chain that can be joined by double bonds, as in unsaturated fatty acids, or single bonds ...

They serve as an energy source for maintenance, milk production, body weight gain and performance. Fats can be defined as compounds that have a high content of long-chain fatty acids (FA) including ...

Get Instant Summarized Text (Gist) Genetically engineered yeast has been developed to produce high levels of punicic acid, a beneficial fatty acid primarily found in pomegranates. This method ...

(Sagimet, Nasdaq: SGMT), a clinical-stage biopharmaceutical company developing novel fatty acid synthase (FASN) inhibitors designed to target dysfunctional metabolic and fibrotic pathways ...

President Donald Trump has nominated Neil Jacobs as administrator of the National Oceanic and Atmospheric Administration—the same acting chief who was overseeing the agency during the ...

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