Anti-neutrophil cytoplasmic antibodies (ANCA) were originally described in the context of chronic inflammatory diseases. Such antibodies were detected by indirect immunofluorescence (IIF) on ...

2020). In contrast to other tissue-based techniques used to quantify immune and tumour cells, such as flow cytometry and RNA sequencing (RNAseq), multiplex immunofluorescence has the advantage of ...

The functional readout of the pathway is activation through mono-ubiquitination of FANCD2 leading to nuclear foci of repair. We have recently developed an FA triple-staining immunofluorescence based ...