Recent studies in Drosophila have described two membrane-associated proteins that regulate Hippo pathway activity 9: Merlin (Mer, NF2 in mammals) and Expanded (Ex, FDM6 in mammals), both of which ...
Recent studies using genetically engineered mouse strains have shed new light on this problem; the Hippo signalling pathway, first elucidated as a regulator of organ size in Drosophila ...
The Hippo pathway is a group of proteins that work together to control organ size and cell fate, and exists in all multicellular animals on Earth. In addition, when it is mutated in humans it can ...