causing fibroblasts to release endogenous antigens that may be cross reactive with exogenous antigens. We made a predictive dynamic map of the corresponding extracellular network. In silico, this map ...

Although the above examples all rely on macroautophagy, chaperone-mediated autophagy also contributes to MHC class II-restricted presentation of endogenous antigens 52. In this case, lysosome ...

largely due to the lack of knowledge of the antigen pertinent for Treg function in human disease. It was therefore important to use novel approaches in order to directly address how “real” endogenous ...

DNA adducts produced by exogenous and endogenous aldehydes are currently becoming recognized as potential tools for studying a variety of human diseases, as well as the effects of air pollution ...

As the main interface with the environment, the skin is placed in the hazardous position of routine exposure and assault from exogenous chemicals and physical agents. Fortunately, most of these ...

Department of Hepatobiliary Surgery, Hebei International Joint Research Center for Digital Twin Diagnosis and Treatment of Digestive Tract Tumors, Baoding Key Laboratory of Precision Diagnosis and ...

This review explores the physiological and pathophysiological role of endogenous nitric oxide in the airways ... NO and airway smooth muscle proliferation In vitro studies have recently shown that ...

Innate lymphoid cells (ILCs) resemble lymphocytes, but lack the key characteristics of adaptive immune cells, namely an antigen-specific receptor. ILCs interact closely with IECs and fulfil an ...

Corticosteroids inhibit antigen presentation ... In physiologic doses, corticosteroids are used to replace deficient endogenous hormones. In pharmacologic doses, corticosteroids have both ...

Antigen unmasking was performed using a citrate buffer (0.01 M sodium citrate pH 6) in a water bath at 95°C for 20 min followed by cooling in distilled water. Tissues were covered with some drops of ...

Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.