it has been found that GSDMD and GSDME related to pyroptosis are widely distributed in tissues such as placenta, heart, brain, intestine, and kidney (Ruan et al., 2020). Inhibition of pyroptosis seems ...

These DAMPs can in turn recognize PRR on surrounding neutrophils and activate PAD4, GSDMD to promote NET formation. NETs components such as H3, MPO, or DNA can further activate immune cells and ...

This valuable study on strategies used by Pseudomonas to subvert hots immunity identifies a new immune evasion strategy. The study presents solid evidence on the cleavage of VgrG2B by Caspase 11 and ...

This valuable study on Pseudomonas subverting host immunity identifies a new immune evasion strategy. There is solid evidence for the cleavage of VgrG2B by Caspase 11 and the generation of fragments ...

Request permissions for this article. Department of Neurology, Sun Yat-Sen Memorial HospitalSun Yat-sen University Guangzhou 510120 China Brain Research Center, Sun Yat-sen Memorial HospitalSun ...

敲除 pir-hsa-216911 导致细胞焦亡活性增加，从而激活了 caspase-1 和 GSDMD。进一步分析表明，pir-hsa-216911 通过抑制与 HCC 细胞焦亡相关的关键基因 TLR4 ...

Could nanotechnology improve exercise performance? Evidence from animal studies Lima, M.R. Moreira, B.J. Bertuzzi, R. Lima-Silva, A.E.