The development of epilepsy, a process known as epileptogenesis, often occurs later in life following a prenatal ... and contribute to neuronal dysfunction by several mechanisms including alterations ...

During a crosstalk between the nervous system and the immune system these modes of cellular communication and the downstream signal transduction events are influenced by neurotransmitters present in ...

Epileptogenesis is the process of developing epilepsy after an initial insult. Seizure susceptibility is enhanced in the early years of life. GABA, normally an inhibitory neurotransmitter ...

Increasing gamma-aminobutyric acid (GABA) and balancing glutamate, brain chemicals called neurotransmitters, may help alleviate symptoms of fibromyalgia (FMS) and chronic fatigue syndrome (ME/CFS).

Seizures could be a marker for a more severe neurodevelopment syndrome, or could reflect a shared substrate. Thalamocortical dopaminergic dysfunction has been linked to seizures and there could be ...

Epilepsy affects around 50 million people worldwide, with 30% of them being refractory epilepsy. This shows that there is still a need for novel anti-seizure medication that have different mechanisms.