Anti-CD20 mAbs were originally created to treat B cell proliferative diseases such as non-Hodgkin's lymphoma and chronic ...

Following acute myocardial infarction, eosinophil counts 5 to 7 days after onset are associated with risk of long-term mortality Eosinophil counts 5 to 7 days after onset in patients with acute ...

TLR7 expression in the lungs was suppressed by allergic inflammation and by interleukin (IL)-5-induced eosinophilia in the absence of allergy. Subjects with moderate-to-severe asthma and eosinophilic ...

Bartolome also highlighted dexpramipexole’s strong differentiation within the competitive landscape. Data from Phase II trials demonstrated therapeutic efficacy similar to biologics, including ...

Methods and results: Mice were treated with chronic restraint stress. A double-labelling approach was taken to localise CRH expression in immune cells (including dendritic cells, mast cells, ...

3 University of Colorado School of Medicine, Aurora, Colorado, USA Objective Eosinophils reside in the colonic mucosa and increase significantly during disease. Although a number of studies have ...

At Microsoft, we are dedicated to helping our customers accelerate AI Transformation by empowering human ambition with Copilots and agents, developing differentiated AI solutions and building scalable ...

Eosinophilic esophagitis (EoE) occurs when white blood cells called eosinophils build up in the esophagus, the tube that moves food and liquids from the throat to the stomach. This buildup of ...

IL-33 has increasingly been shown as a key regulator of type 2 inflammation via signaling through its receptor, ST2. The present study was conducted to detail a method of eosinophil differentiation ...

Pro-inflammatory cytokines that are generated following allergen challenge can impact the differentiation of hematopoietic progenitor cells leading to increased production of effector cells such as ...