At the American Society for Reproductive Medicine 2024 (ASRM) conference in Denver, the session “From Double Helix to Double Trouble: Sperm DNA Fragmentation Unveiled” provided critical insights into ...

New gene therapy modalities, such as CRISPR guide RNA (single guide ribonucleic acid [sgRNA]) and messenger RNA (mRNA), ...

Mitochondrial DNA (mtDNA) is actively removed during spermatogenesis in a conserved process that enforces the uniparental ...

Attribution (BY): Credit must be given to the creator. Endonuclease III (EndoIII), a key enzyme in the base excision repair (BER) pathway, contains a [4Fe4S] cluster that facilitates DNA repair ...

Recent studies have suggested that sperm mitochondrial DNA copy number (mtDNA-CN), DNA fragmentation index (DFI), and reactive oxygen species (ROS) content are crucial to sperm function. However, the ...

CfDNA sequencing was accomplished in 43 eyes (VRL: 23, control: 20), among which 11 samples (VRL: 1, control: 10) underwent enzymatic DNA fragmentation before sequencing; while the remaining 5 eyes ...

enabling the production of custom DNA sequences of up to 500 nucleotides in length with unprecedented sequence complexity. This breakthrough in enzymatic DNA synthesis overcomes traditional chemical ...

1New England Biolabs, Ipswich, MA.

In summary, enalapril significantly mitigated multiple pathological markers associated with aging, including lipid droplets, amyloid, glycogen deposition, and fibrosis, in the brain, kidneys, liver, ...

Learning about your genetics and ancestry is easier than ever. All you need to do is choose from the many DNA ancestry tests available online, receive your kit and send back the required DNA samples.

DNA polymerases carry out crucial functions in many DNA metabolic processes. Polymerases catalyse the addition, using a template, of complementary nucleotides to the 3′ end of DNA primer strands.