This marks the second BTD for petosemtamab in HNSCCUTRECHT, The Netherlands and CAMBRIDGE, Mass., Feb. 18, 2025(Nasdaq: MRUS), a clinical-stage oncology company developing innovative, full-length mult ...

BTD designation follows the initial receipt of BTD and Fast Track designation for petosemtamab for the treatment of patients with r/m HNSCC whose disease has progressed following treatment with ...

Through its PROTAC (PROteolysis Targeting Chimera) protein degrader platform, Arvinas is pioneering the development of ...

To this end, recent clinical and preclinical studies have implicated the epidermal growth factor receptor signaling pathway in chronic pain states. EGFR is one of four members of the ErbB family of ...

Etern Biopharma (Shanghai) Co. Ltd. has identified proteolysis targeting chimeras (PROTACs) comprising an E3 ubiquitin ligase binding moiety coupled to an androgen receptor targeting moiety through a ...

Arvinas Inc. (NASDAQ:ARVN), a biotechnology company specializing in protein degradation therapeutics, stands at a critical juncture as it approaches the release of pivotal clinical trial data.

The general linear models were adjusted for the baseline levels of the urinary or serum biomarkers if follow-up data were tested and additionally for sex, age, body mass index (BMI), eGFR, smoking and ...

It was a weekend to remember for 18-year-old Rayan Ahmed (EGF) as he stormed to victory at the Yas Links Abu Dhabi Men's Open, finishing three shots ahead of a charging Oscar Craig (TFA ...

Battery degradation is a thing - and for many people, it's a reason why they are scared to buy an EV. Tesla, Inc. is an American electric vehicle manufacturer largely attributed to driving the EV ...

we found that ADM2 facilitates the expression of insulin-like growth factor 2 (IGF-II), which then triggers the activation of the AKT-GSK3β-mTOR signaling pathway via the IGF-II receptor (IGF-IIR ...