The image is a time projection of mitochondria (in the cytoplasm, grey) and chromosomes (center of the cell, orange) during anaphase showing a flow pattern with vortexes. The flow pattern is aligned ...

1 Institute for Advanced Research, Nagoya University, Nagoya, Japan 2 Department of Biological Science, Graduate School of Science, Nagoya University, Nagoya, Japan Faithful chromosome segregation is ...

This important work provides another layer of regulatory mechanism for TGF-beta signaling activity. The evidence supports the involvement of microtubules as a reservoir of Smad2/3, however, additional ...

Objectives: Spinal muscular atrophy with lower extremity predominance 1 (SMALED1) and Charcot–Marie-Tooth diseasetype 2O (CMT2O) are two kinds of hereditary neuromuscular diseases caused by DYNC1H1 ...

In eukaryotic cells, intracellular components are organized by the microtubule motors cytoplasmic dynein-1 (dynein) and kinesins, which are linked to cargos via adaptor proteins. While ~40 kinesins ...

The cytoskeleton is a network of filamentous and tubular protein structures that support cell shape, intracellular compartmentalisation and trafficking, cell migration and cell division. The key ...