The reduction of Notch levels within the lymph gland plasmatocyte population reduces crystal cell number. This extension of a transdifferentiation mechanism reinforces the growing role of ...

Mutations in GlcT compromise Notch signaling in the Drosophila intestinal stem cell lineage resulting in the formation of enteroendocrine tumors, and preliminary data suggests that a homolog of ...

Signalling between Notch receptors and ligands influences many differentiation processes and cell-fate decisions during embryonic and postnatal development. Stem-cell maintenance, binary cell-fate ...

NOTCH signaling plays a crucial role in tumorigenesis and therapeutic resistance, with its activation linked to drug resistance in various cancers. The NOTCH family includes four receptors (NOTCH1 ...

It would be reasonable to say that Markus “Notch” Persson, the 45-year-old Swedish creator of Minecraft, has played life in both modes now – once as a shy, workmanlike coder; then as a man ...

Noised-induced hearing loss (NIHL) is an acquired, progressive neurological damage caused by exposure to intense noise in various environments including industrial, military and entertaining settings.

Morgan's experiments are not only fundamental to our knowledge of heredity; they have also made an animal respectable for science, which previously only a few specialists had worked with: the fruit, ...

The Notch signaling pathway plays an important role in various physiological and pathological processes, particularly in fibroblast activation. miR - nine in exosomes can indirectly reduce the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. During their growth, plants encounter and ...