Right open reading frame kinase 2 (RIOK2) plays an essential role in ribosome assembly and cell growth, survival and stress responses. Research has linked RIOK2 to tumor progression and poor prognosis ...

Orphan Drug Designation follows positive Phase 1 data presented at the 12th International Workshop on Waldenström ...

We sell different types of products and services to both investment professionals and individual investors. These products and services are usually sold through license agreements or subscriptions ...

Want a no-equipment abs exercise that can be done anywhere—but *so over* basic crunches? Enter: the V-up. Also known as a jackknife, the bodyweight move recruits the entire core and provides a ...

An experimental drug developed by the biotech firm Arvinas and Pfizer — the first in a class of medicines based on a cell’s natural machinery for eliminating diseased proteins — delayed ...

Visa, Inc. engages in the provision of digital payment services. It also facilitates global commerce through the transfer of value and information among a global network of consumers, merchants ...

New agents targeting endocrine therapy and CDK4/6 resistance in hormone receptor–positive breast cancer are in development.

随着FDA批准的ADC药物越来越多，受到鼓舞的开发商们明显地加大了对ADC管线资产的投资力度。ADC正在重新定义靶向癌症治疗的前景。ADC的发展，在抗体、有效载荷和接头的开发设计方面都实现了迭代更新。自从2000年首款ADC药物Mylotarg(ge ...

Other recent partnerships in the molecular glue degrader category include Takeda's recent $1 billion-plus link-up with Degron Therapeutics, a $1.46 billion deal between Novo Nordisk and Neomorph ...

A degrader molecule, either PROTAC or molecular glue, brings the protein of interest (POI) and E3 ubiquitin ligase in close proximity and engages the ubiquitin-proteasome system (UPS), the cellular ...