There are few human diseases that have been linked to mutations or defects in DNA polymerases. Mutations in the polymerase that replicates mitochondrial DNA, Pol γ, lead to a range of human ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...

RNA polymerase binds to a region just before the gene, called the promoter, before moving down the DNA to the gene. Enhancers are regions of DNA that act as ... “Our work demonstrates the power of ...

Now, researchers used cryoelectron microscopy (cryo-EM) to elucidate the structure of the Nipah virus polymerase complex (the large protein and phosphoprotein). Not only that, but they also ...

Scientists at deCODE genetics have unveiled a groundbreaking map of human DNA mixing during reproduction, offering insights into genetic diversity, health, and fertility. Credit: SciTechDaily.com ...

Hangzhou Synrx Therapeutics Technology Co. Ltd. has described DNA polymerase θ (POLθ) inhibitors reported to be useful for the treatment of cancer.

Jan. 30, 2025 — The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was ...

The method made it possible to map the human genome ... How did the discovery of the Taq polymerase result in this important research technique? To amplify a DNA fragment, scientists need to ...

Comparison of that ancient DNA with modern human DNA showed that the two species had interbred and that people today still carry the genetic fingerprint of that intermixing. Since then ...