The methylation of plasma cell-free DNA (cfDNA) has emerged as a valuable diagnostic and prognostic biomarker in various cancers including colorectal cancer (CRC). Currently, there are no biomarkers ...
Endometrial cancer (EC), one of the most common gynecologic malignancies worldwide, poses a significant burden particularly among young women, with poor treatment outcomes and prognosis for advanced ...
DNA methylation is the covalent addition of methyl ... type and severity of cancer, linked to a relevant DNA hypomethylation signature. CDX2 binds distinct targets in developing and adult ...
Recent research gathered evidence suggesting that DNA methylation can serve as a "dimmer ... focused on its contribution to some types of cancer, neurological disorders and overall mental health ...
This review discusses the intricate mechanisms underlying cancer epigenetics, unraveling the complex interplay between DNA methylation, histone modifications, chromatin remodeling, and non-coding RNAs ...