DNA methylation is the covalent addition of methyl groups to DNA bases, typically the cytosine of CpG dinucleotides. It is catalyzed by methyltransferase enzymes using a S-adenosyl methionine ...

Notably, DNA methylation, an important epigenetic regulatory mechanism, often manifests as global hypomethylation or hypermethylation of specific gene promoter regions in BC. Alterations in this ...

DNA methylation microenvironment of Munro's microabscess and the crosstalk with transcription and its effect on neutrophils have not yet been revealed. Methods: Performed genome-wide DNA methylation ...

Dunn, recently carried out a study exploring how DNA methylation, an epigenetic modification that entails the addition of a methyl group to the DNA, contributes to the well-documented relationship ...

Epigenetic clocks that quantify rates of aging from DNA methylation patterns across the genome have emerged as a potential ... which was trained on data from several tissues and cell types to ...

The methylation of plasma cell-free DNA (cfDNA) has emerged as a valuable diagnostic and prognostic biomarker in various cancers including colorectal cancer (CRC). Currently, there are no biomarkers ...

College of Animal Science and Technology, Southwest University, Chongqing 400715, China College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China ...

In a nutshell Scientists discovered that random DNA mutations don’t just cause local damage, they trigger widespread changes ...

A new study has uncovered a direct link between somatic mutations and epigenetic modifications, challenging established views ...

Serum mucin 5AC (MUC5AC) as a predictor of outcomes and microscopic distant metastasis in pancreatic ductal adenocarcinoma (PDA). This is an ASCO Meeting Abstract from the 2025 ASCO Gastrointestinal ...