吸烟会通过损伤机体DNA来引起癌症，目前科学家们对 肺癌 的测序工作发现了与暴露烟草烟雾致癌物苯并 [a]芘 (benzo [a]pyrene)有关的突变特征，苯并 [a]芘能在细胞中代谢成为苯并 [a]芘二醇环氧化物 (BPDE,benzo ...

The study from The Hebrew University of Jerusalem, led by Prof. Sheera Adar and her graduate student Elisheva Heilbrun-Katz ...

LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means ...

For this reason, they are at greater risk of accumulating damage and must develop alternative repair pathways to avoid dysfunction. Scientists do not understand how neuronal DNA damage is ...

Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals. For women, ...

Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals. For women, that can lead to poor egg quality, which in turn can cause infertility, ...

Cigarette smoke causes cancer primarily by damaging the DNA. A new study that mapped these damages has revealed that the way ...

In addition, there are a handful of syndromes with an etiological link to DNA damage and repair that exhibit symptoms of accelerated aging but have no striking neurological symptoms. Such ...

Cigarette smoke causes cancer primarily by damaging the DNA. A new study that mapped the DNA damages caused by smoking, ...

Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals. For women, ...

The study, published in Nucleic Acids Research, focused on benzo (a)pyrene, a toxic chemical in cigarette smoke, which binds to DNA when processed by the body, and disrupts its normal function and ...