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综述:免疫细胞代谢对膜性肾病的影响及前瞻性治疗
硫酸脱氢表雄酮(DHEAS)在 IMN 组中显著下调,类固醇激素代谢紊乱降低了 DHEA 和 DHEAS 水平,诱导 Treg 细胞活性,进而导致 Th1 型细胞因子产生,干扰 Th2 型细胞因子合成。 目前研究表明,代谢重编程促进 MN 中促炎 T 细胞的激活和分化。除了 ATP 合成,代谢重编程 ...
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