“These de novo design peptides are cyclic-composed of non-natural amino acids and are the third generation of peptide therapeutics,” Lerner said. “The new generation of peptide drugs ...

BEIJING, Jan. 8, 2025 /PRNewswire/ -- In a recent achievement, DP Technology's hit discovery platform RiDYMO® has successfully designed a cyclic peptide targeting β-catenin, a historically ...

With AND-gate logic, two distinct inputs are required for an output. Accordingly, the researchers engineered cyclic peptides—small amino acid chains—to respond only when they encounter two ...

They tested five optimized pairs in E.coli, playing with individual or combined pairs, and produced more than 100 new cyclic peptides, each containing up to three ncAAs. “[The study] is definitely ...

Dr. Mazzo’s presentation is scheduled for Monday, February 10 th at 2:00 p.m. Eastern Time. For more information about the conference and how to register, please visit ...