Here the authors report that excessive mtROS induces the release of mitochondrial PGAM5 into cytoplasm and subsequent dephosphorylation of MST3 kinase, promoting colorectal cancer progression.

The approach requires balance, however. There is the risk of increased AEs, as well as financial toxicity. Friedlander shared ...

Despite the established links between inflammation and cancer development, the effects of inflammatory signaling on cancer ...

Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...

If the mean base quality falls below 15, the sequence is truncated at that particular ... construed as a potential conflict of interest. Aade, advanced adenoma; AUC, area under curve; AVD, average ...

If you’re one of the 155,000 Americans who develop colorectal cancer this year, you’ll likely experience a roller coaster of emotions. Colorectal cancer occurs when cells in the colon or ...

Isabella Strahan, the daughter of "Good Morning America" co-anchor Michael Strahan is opening up about the biggest lesson she learned after being diagnosed with a malignant brain tumor.

Colon cancer is one of the most prevalent cancers globally, especially among adults over 45. Crucial in prevention and early detection, maintaining a healthy diet and consuming gut-friendly drinks ...

Figure 5: Telomere dysfunction peaks at the adenoma-carcinoma transition in human colorectal carcinogenesis. Whole-mount staining/analysis of micro- and macroadenomas. The complete small and large ...

the role of the gut microbiota and its dysbiosis in colorectal tumorigenesis has been emphasized. Metagenomics and amplicon-based microbiome profiling provided insights into the potential role of ...

Moores Cancer Center, University of California San Diego, 3855 Health Sciences Drive, #0901, La Jolla CA 92093-0901, USA; e8martinez{at}ucsd.edu Objective For individuals with 1–2 small (<1 cm) ...

Objective Sessile serrated adenomas (SSAs) are the precursors of at least 15% of colorectal carcinomas, but their biology is incompletely understood. We performed a clinicopathological and molecular ...