Furin is identified as the key enzyme responsible for cleaving the apelin precursor. Inhibiting this cleavage could serve as ...

Scientists Discover How Excessive Red Meat Consumption Increases Colorectal Cancer Risk Oct. 23, 2024 — Scientists have uncovered a critical link between the overconsumption of red meat and an ...

Expert Rev Mol Diagn. 2009;9(2):125-137.

Optimal glycaemic control at baseline was defined as mean haemoglobin A1c (HbA1c)<7%. Outcomes of interest included colorectal cancer (CRC) and colonic adenoma development. We used propensity score ...

Here the authors report that excessive mtROS induces the release of mitochondrial PGAM5 into cytoplasm and subsequent dephosphorylation of MST3 kinase, promoting colorectal cancer progression.

A large number of studies have shown that the human microbiome plays a critical role in tumorigenesis, tumor progression ... SAHMI tool for mining microbial sequence information and single ...

These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...

Objective Early-onset colorectal cancer (CRC) is increasing in the USA despite rapid declines in older ages. Similar patterns are reported in Australia and Canada, but a comprehensive global analysis ...