Results The p53 mutation acts as a switch to expand progenitor cells and inhibit their differentiation towards metaplasia, but only amidst chronic injury. In L2-IL1β mice, p53 mutation increased ...

The natural coagulation process results in stable platelet activation and the slow release of growth factors. Methods: In our study, primary human endometrial stromal cells (hESCs) were extracted from ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

Jan. 23, 2025 — There's a downside to being a powerful alpha male -- at least if you're a baboon. Studies show that despite their high rank, the No. 1 males in baboon society are also some of ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

Stem cells play a crucial role in re-establishing homeostasis in the body ... particularly with regard to the lack of clear evidence to fully characterize their potential therapeutic sequelae.

Uterine fibroid pain originates from non-cancerous tumors that grow in a person's uterus. The growths can vary in size and can cause different types of painful symptoms. According to MedlinePlus ...

Monoclonal antibodies against P-cadherin can carry a drug payload to the cancer cells. It has not been clear, though, exactly how the antibodies attach to P-cadherin or how they get inside the ...

Cell signalling is the mechanism by which stimuli are transmitted via a signalling cascade to effector molecules that orchestrate the appropriate response. Types of cell signalling pathways ...

Managing endometrial cancer can be very stressful. Taking steps to support your emotional and mental health is important for improving your quality of life with this condition. An endometrial ...

Bone-marrow-derived multipotent progenitor stromal cells — or mesenchymal stem cells ... Therefore, it is clear that none of these molecules has an exclusive role and that MSC-mediated ...

Now, researchers at University of California San Diego have discovered how healthy stem cells are transformed into cancer stem cells in the earliest stages of the disease. Oral cancer - also known ...