[12,19] In addition to optimizing intravascular volume, nephrologists usually prescribe antihypertensive drugs. A national survey found that 75% of new hemodialysis patients and 60% of patients ...

Numerous double-blind, randomized, placebo-controlled studies have documented that antihypertensive drug therapy reduces cardiovascular events in older adults. In the Hypertension in the Very ...

Idorsia Pharmaceuticals has claimed FDA approval for aprocitentan as a treatment for resistant hypertension, becoming the first drug in the endothelin receptor antagonist class for that indication.

So, the UK government is considering reclassing ketamine as a Class A drug. The Home Office asked the Advisory Council on the Misuse of Drugs to “carefully consider” the issue. Do you think ...

The association between systolic blood pressure and all-cause mortality differs between frail and nonfrail individuals, highlighting uncertainties about the effectiveness of antihypertensive ...

In the third conditional logistic regression model, which was constructed according to the use of FRIDs, falls during hospitalization were more common among users of antihypertensive drugs, ...

The government is considering reclassifying ketamine as a Class A substance after a record number of people reported using the drug. Ketamine is currently a Class B substance, meaning the maximum ...

First-in-class drugs are therapies that utilize novel mechanisms of action, offering new approaches to challenging diseases. In 2024, the U.S. Food and Drug Administration (FDA) approved 50 new ...

The purpose of this guidance document is to provide an understanding of the factors that guide classification decisions by Health Canada in relation to external use products which may share ...