Structural variation in the genome can directly or ... reference assembly should be that it encompasses the longest chromosomal sequences, including polymorphic regions that might be absent ...

Although HR provides vital repair mechanisms, it is also hazardous, as revealed by the many ways in which it can lead to chromosomal structural change, including copy number variation. HR repair ...

Chromosomal microarray analysis (CMA), a method of genome-wide detection with high resolution, has been recommended as a first-tier test for prenatal diagnosis, especially for fetuses with structural ...

However, chromosomal variation is ubiquitous in some newly developed synthetic hexaploid wheat ... In both SHW-L1 (A:B:D = 4:21:4) and its hybrids chromosome structural variations were biased toward ...

Analysis of Structural Variation events has been done in the 1000 Genomes project and similar project as GoNL on population scale. These projects provided good insights into the characteristics of ...

The work opens the door to studying and predicting the role of structural variation in disease. Structural variation is a change in the structure of an organism's genome, such as deletions ...

The X and Y chromosomes, commonly referred to as the sex chromosomes, are one such pair. They determine the biological sex, reproductive organs, and sexual characteristics that develop in a person.

They also constructed a comprehensive genomic variation map by resequencing 177 celery samples. This study was published in Plant Biotechnology Journal. Through phylogenetic, population structure ...

The last few years have provided us with a new level of understanding of how chromosomes are replicated, segregated and read - and how their 3D organisation influences expression of individual genes ...

Cephalopods may have the oldest sex chromosomes of any animal, according to a new discovery in the octopus genome. That's a big deal given that scientists didn't know until now if these oddball ...

In humans, female cells contain two X chromosomes (XX) and male cells contain one (XY). In each female cell, one X chromosome must be inactivated—crumpled ...

Call and score variants from WGS/WES of rare disease patients.