Injury resulting from 1 mM hydrogen peroxide could be reduced by either coincubation of cells with 1,10-phenanthroline, an Fe2+ chelator, or preincubation with deferoxamine, and Fe3+ chelator, ...

Polyphosphate (polyP) exists in all life forms; however, its biological functions in metazoans are understudied. Here, we explored Drosophila as the first genetic model to explore polyP biology in ...

Q4 2024 Earnings Call Transcript March 7, 2025 Operator: Good morning, and welcome to the Molecular Partners Fourth Quarter ...

To confirm that copper was the driving force behind these effects, the researchers used a copper-selective chelator — a compound that binds to copper and prevents it from interacting with cells.

It involves some protein engineering, but it also certainly involves the linker chelator. And of course, we also do half-life extenders. Most importantly, however, for the patient's benefit ...

Journal of Nuclear Medicine February 2025, jnumed.124.268835; DOI: https://doi.org/10.2967/jnumed.124.268835 ...