Drug addiction is a condition in which there is uncontrolled use of a substance with a harmful outcome. Drugs overstimulate the brain’s reward circuit, producing pleasure or euphoria. With repeated ...

The 2024 body horror film The Substance is written and directed by Coralie Fargeat. It centres on Elisabeth Sparkle (Demi Moore), a fading celebrity who uses an illegal substance that produces a much ...

There's always a breakout movie at the Cannes Film Festival, and among the festival's 2024 new movie it was The Substance from Coraline Fargeat and starring the popular 90s actress Demi Moore, in what ...

Drs Harrington and Gibson review their picks for the top cardiology trials of 2024 and look ahead to 2025, particularly what health topics may be prioritized by the new administration.

Spoilers ahead. The Substance is an on-the-nose parody of celebrity beauty standards especially as they apply to aging female stars. The entire movie—which is a grueling 142 minutes long ...

Addiction can reveal itself in physical signs, as well as psychological and behavioral ones, although they are not diagnostically specific for the condition. Substance users may have dilated ...

It’s a striking coincidence that two much talked-about current works of popular culture — the Apple TV+ series “Severance” and the film “The Substance,” starring Demi Moore — both ...

Coralie Fargeat tells IndieWire how films by Stanley Kubrick, David Lynch, David Cronenberg, the Coen brothers, John Carpenter, and Darren Aronofsky left their imprint on her and "The Substance." ...

Around the world and in the U.S., nicotine is the most widely used addictive substance; tobacco causes a reported 40 million deaths worldwide. According to the National Institute of Drug Abuse ...