cGAS-STING senses cytosolic double-stranded DNA and triggers an innate immune response ... The first step in tumorigenesis is the transformation of a pre-malignant cell into a neoplastic precursor, ...

Centromere defects, chromosome instability, and concomitant cGAS-STING pathway activation correlate with increased fibrosis markers, suggesting that the cGAS-STING pathway is linked to immune ...

Recognition of nucleic acids by DNA sensors induces IFN-I and interferon-stimulated genes (ISGs), but the involvement of cyclic guanosine monophosphate (GMP)–AMP synthase (cGAS) and stimulator of ...

基于此，西南医科大学的吴安国教授与重庆市中医院的任放副研究员，深入探讨了线粒体自噬与cGAS–STING信号通路之间的相互作用。这一研究揭示了细胞在应激状态下如何通过这些机制维持稳态。具体而言，线粒体自噬是清除受损线粒体的关键手段，而cGAS–STING ...

尤其是西南医科大学药学院的吴安国教授和重庆市中医院的任放副研究员课题组对线粒体自噬与cGAS–STING信号通路的深入研究，为我们理解神经炎症提供了新的视角。本篇文章将借此探索这些机制的互动关系以及它们在神经退行性疾病中的重要性。 1. 神经炎症的 ...

Sting from a scorpion Onset of local pain and tingling after a scorpion is seen in the area The main symptoms are pain, tingling and numbness at the sting site About 85% cause only local symptoms at ...

Request permissions for this article. Department of Neurology, Sun Yat-Sen Memorial HospitalSun Yat-sen University Guangzhou 510120 China Brain Research Center, Sun Yat-sen Memorial HospitalSun ...

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A phenomenon upon release, ‘Desert Rose’ was an inspired fusion of Algerian folk music and contemporary electronica that became a high-water mark for Sting. Alluring and sensual, Sting’s ...