Our News & Views discussed a recent paper 6 that clearly stated that the existence of a putative membrane ... receptor couples to a common intracellular signaling pathway in four different cells ...

Alterations in thyroid gland function result from the action of stimulating or blocking autoantibodies on cell membrane receptors. Three principal thyroid autoantigens are involved in AITD.

Almost 35% of drugs approved by the Food and Drug Administration work by targeting G protein-coupled receptors (GPCRs), proteins embedded in cell membranes that allow cells to communicate with ...

Researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced stability and signaling, paving the way for novel drug ...

EPFL researchers have developed a computational method to explicitly consider the impact of water while designing membrane ...

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...

Glycoproteins typically bind to receptors on the membrane of a host cell. Viruses that do not bud from the host cell membrane do not have an envelope, so they are called “naked” or ...

A team led by UT Southwestern Medical Center researchers has identified a key mechanism responsible for endosomal recycling ...

Adhesion G protein-coupled receptors (GPCRs) are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for ...