Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

So far, Fiore's new direction is paying off. The extracellular matrix supports and gives structure to our cells and tissues: It provides a scaffold for cells to grow in, dictates the mechanical ...

Laboratory for Research on the Structure of Matter (LRSM), University of Pennsylvania, Philadelphia, United States ...

Researchers identified two anoikis-related genes linked with CTEPH, and that may serve as diagnostic biomarkers or treatment ...

LATS1/2-inactivation and consequent nuclear YAP/TAZ hyperactivation in the mammary epithelium drives the development of a pro ...

quiescent cells whose main functions is to store vitamin A and probably to maintain the normal basement membrane-type matrix. However, numerous in vivo and in vitro studies indicate that in ...

Feb. 10, 2025 — Influenza A virus particles strategically adapt their shape -- to become either spheres or larger filaments -- to favor their ability to infect cells depending on environmental ...

This article examines viral and non-viral vectors in gene therapy, highlighting their mechanisms, advantages, and limitations ...

Membrane biophysics is the study of the physical ... and the effect they have on paracellular transport and phenomena relating to cell shape. MD simulations and experiments in cells reveal core ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

Cell membrane Allows gases and water to diffuse freely into and out of the cell. Controls the transport of other molecules. Mitochondrion (plural is mitochondria) Contains enzymes for the ...

Oxide-ion conductors are important energy materials. Here, the authors found a tellurite-based oxygen ion conductor highlighting the interplay of secondary bond interactions and Grotthuss-like ...