Scientists discover that the CD74 protein could predict the effectiveness of immunotherapy, advancing colon cancer treatment.

Using a cutting-edge technique called spatial transcriptomics, they observed that T cells stimulated nearby macrophages and tumor cells to produce a protein called CD74 and that tumors that were ...

The results suggest that measuring CD74 levels could predict whether someone with bowel cancer will respond to immunotherapy, independent of which type they have.

Researchers have shown that the amount of a protein called CD74 can indicate which people with bowel cancer may respond best to immunotherapy. Researchers at the Francis Crick Institute and Barts ...

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled "Acquired RUFY1-RET rearrangement as a mechanism of resistance to lorlatinib in a patient with CD74-ROS1 ...

近日，英国弗朗西斯·克里克研究所（FCI）团队在 Cancer Cell 期刊发表了最新研究成果 ...

伦敦玛丽女王大学弗朗西斯克里克研究所和巴特癌症研究所的研究人员已经证明，一种名为CD74的蛋白质的含量可以表明哪些肠癌患者对免疫治疗的反应最好。 蛋白水平预测肠癌免疫治疗反应 ...

Furthermore, CD74 (a MIF-binding protein) was implicated in CXCR2-mediated MIF-induced arrest. To test whether MIF can directly elicit leukocyte chemotaxis through these receptors, the authors ...

They found that the levels of expression of a protein called CD74 can predict response to immunotherapy, independent of subtype. The team first studied the immune cells surrounding different ...

Researchers at the Francis Crick Institute and Barts Cancer Institute, Queen Mary University of London, have shown that the amount of a protein called CD74 can indicate which people with bowel ...