Magrolimab has been at the forefront of drugs targeting CD47, a protein expressed on cancer cells that sends out a ‘don’t eat me’ signal to macrophage cells of the immune system, and was the ...

Mar. 12, 2025 — A new study analyzing diet, average plasma sugar levels and cancer prevalence in some 273 vertebrate species showed surprising results. The study found no significant link ...

Other studies of the CD47-directed antibody in large B cell ... been established as a "don't eat me" signal that prevents the cancer being attacked by white blood cells called macrophages.

Cancer researchers at Children's Medical Research Institute have discovered an "unexpected mechanism" that our cells use to avoid cancer.

*仅供医学专业人士阅读参考我们知道，在一些血液系统恶性肿瘤中，HDAC抑制剂（HDACi）表现出了不错的疗效，但在实体瘤方面，HDACi的疗效确实有点不尽如人意，这与其耐药问题有关。既往有研究显示，肿瘤微环境的改变可能是导致HDACi耐药的一个因素， ...

Recently announced positive data from pivotal randomized, placebo-controlled phase 3 clinical trial of CAN-2409 in ...

Dying from colon cancer in the end stage means that treatments are no longer working or need to be stopped due to side effects. The cancer has spread throughout the body, and the condition is ...

Throw yourself into a creative project today. Your inner child wants to play when the moon and Mars harmonize. Expressing your artistic license? Take risks to color outside the lines. Having the ...

Story March 18 - Pyxis Oncology: Having recently trimmed back its pipeline to a sole cancer candidate ... its cash into further trials of its CD47 blocker, the company will lay off 30% of its ...