This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Copyright: © 2025 Elsevier Ltd. Published by Elsevier Ltd. CAR T-cell therapies have revolutionised treatment of many diseases, but their expense means many patients ...

The research team suggests that the expression of CD44 may have increased in response to inflammatory cytokines, which are signal molecules secreted by other cells, or that SARS-CoV-2 infection ...

Newly diagnosed HT patients showed higher proportions of CD8 + CD28- T cells than the other HT patients (p < 0.05) (Figure 1A). Proportions of CD45RA + CD62L + were lower in HT within the CD8+ T ...

Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans. Nature Microbiology , 2025; DOI: 10.1038/s41564-024-01903-7 Cite This Page : ...

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Oncolytic adenoviruses were designed to reach potent intratumoral T-cell activation via expression of bifunctional-T-cell engagers (MATEs). MATEs consist of a CD3 binding domain to bind T cells and a ...

Figure 1: γ c-dependent lymphokines are required for the peripheral survival of naïve CD4 + T cells. Figure 3: Antigen-driven proliferation of CD4 + T cells is independent of γ c-cytokines.

In the same way that ChatGPT understands human language, a new AI model developed by computational biologists captures the language of cells to accurately predict their activities. In the same way ...

2024年12月，中山大学医学院张旭东、侯琳琳教授团队在期刊【Nano Today】上发表题为“In situ engineering of mRNA-CAR T cells using spleen ...