At the time of B cell recovery, the IgD +, CD27+ memory B cell subset was significantly larger in the nonresponder group. Within the group of 12 responders, 6 patients experienced an early relapse ...

Division of Rheumatology, University of Washington, Seattle, WA, United States Objectives: To investigate whether biomarkers related to B cell activation and autoantibody production are associated ...

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Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease caused by a novel phlebovirus (SFTS virus (SFTSV)) (1). Clinical manifestations of SFTS include fever, ...

Objective Combination therapy with rituximab and belimumab is a novel treatment strategy for severe SLE and lupus nephritis.

Variability in Biological Response to Rituximab: What Does It Mean & Why Does It Matter? B cells involved in or driving the pathogenesis of autoimmune diseases are referred to as autoreactive B ...

1 Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, United States of America 2 Harvard Medical School, Boston, MA, United States of America 3 Rheumatology Unit, Massachusetts General Hospital, ...

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