Systemic lupus erythematosus (SLE) is a heterogeneous multisystem inflammatory disease with wide variability in clinical manifestations. Natural arising CD4+ regulatory T cells (Tregs) play a critical ...

One possible mechanism by which the Th17/Treg balance is disturbed in psoriatic lesions attributes to the high levels of IL-6. And Tfh cells, which has been proved to be one of the major sources of IL ...

GCs are segregated into dark zones, in which B cells proliferate and mutate their antibody receptors, and light zones, in which B cells undergo selection processes through interactions with Tfh cells ...