Researchers investigate the sex-dependent microglial response to a colony-stimulating factor 1 receptor (CSF1R) inhibitor.

Contrary to prior data, this study shows that neither eosinophils nor STAT6-mediated IL-4/IL-13 signaling contribute ...

These processes are genetically controlled and depend both on the history of cells (lineage) and on the activities of signalling pathways, which coordinate the cell interactions leading to ...

Microglia, the brain’s immune cells, play vital roles in clearing toxins and maintaining neuronal health but can also contribute to neurodegenerative diseases if overactive.

The study's findings are crucial in the rapidly emerging field of developing disease-modifying therapies that target microglia.